A Periodontal Expert: Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects

Emdogain® is the biology-based and scientifically proven solution to promote the predictable regeneration of hard and soft tissues lost due to periodontal disease like intrabony defects, class II mandibular furcation and recession defects. ReliableMore than 40 clinical studies, involving 1500 intrabony periodontal defects in 1200 patients, have demonstrated that Emdogain is effective in stimulating the formation of new periodontal attachment in soft and hard tissue. 60-70% defect fill was measured as a gain of radiographic bone one year following treatment with Emdogain. Simple treatment with Emdogain requires little or no preparation time; no mixing and no specialized products or equipment are necessary. It is convenient and effective to use in areas difficult to treat such as interproximal areas, defects distal to the second molar, defects located under bridgework and wide defects. No second surgery is required.VersatileThe possibility for the use of Emdogain in periodontal defects is expanding.
It is indicated for:
1-,2-,3-wall defects
Recession defects
Class II mandibular furcation defects

Cochrane Review>>>

By mimicking the biological processes of natural tooth development, Emdogain forms an insoluble three dimensional matrix, which allows for the selective colonization of cells. Through cellular interactions, a cascade of events initiates increased cell proliferation, growth factor synthesis and cell differentiation resulting in the formation of necessary hard and soft tissues such as cementum, periodontal ligament and alveolar bone.
1. Attachment – Mesenchymal cells attach to the formed matrix.
2. Proliferation and growth – The cells spread and populate the surface.
3. Cementum formation – The cells start to produce cementum with insertingcollagen fibers.
4. Alveolar bone – Along the treated root surface, and at a certain distance, a condensation of fibrous tissue indicates the region where new alveolar bone is forming.

Post Surgery one wk:

>>>>>PostSx 2wks>>>>>

**Above Clinical Photo present by @Perio^^^
^How to control the bleeding before your application of Emdogain? Dr. Sculean's suggestions from his Taiwan's lecture!